Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.41 |
| ▸ | ITGAV | P06756 | 17/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481534 | 0.85 | ITGB3 (0.43) | ITGB3ITGAVITGA2BPPARGPPARA | |
| SCHEMBL6474022 | 0.84 | ITGB3 (0.43) | ITGB3ITGAVITGA2B | |
| SCHEMBL6485142 | 0.82 | ITGB3 (0.44) | ITGB3ITGAVITGA2B | |
| SCHEMBL6481139 | 0.81 | SYK (0.38) | ITGB3ITGAVITGA2B | |
| SCHEMBL6481186 | 0.80 | ITGB3 (0.37) | ITGB3ITGAVITGA2B | |
| SCHEMBL6480964 | 0.79 | ITGB3 (0.38) | ITGB3ITGAVITGA2B | |
| SCHEMBL6474654 | 0.78 | ITGB3 (0.43) | ITGB3ITGAVITGA2BEGLN2EGLN1 | |
| SCHEMBL6474857 | 0.76 | ITGB3 (0.43) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6476022 | 0.75 | ITGB3 (0.46) | ITGB3ITGAVITGA2BEGLN2EGLN1 | |
| SCHEMBL8507891 | 0.74 | ITGB3 (0.54) | ITGB3ITGAVITGA2BPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011045-A | Vitronectin receptor antagonists, their preparation and their use | HOECHST AKTIENGESELLSCHAFT | 2000-01-04 | — | — | US | disclosed |