Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307461 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL14141933 | 0.84 | LMNA (0.39) | SMN1; SMN2SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL11818265 | 0.83 | SLC6A2 (0.38) | SMN1; SMN2SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL16266998 | 0.80 | SLC6A2 (0.36) | SMN1; SMN2SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL3309160 | 0.79 | LMNA (0.39) | LMNATHRB | |
| SCHEMBL14142190 | 0.79 | SMN1; SMN2 (0.35) | SMN1; SMN2SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL10928292 | 0.78 | SLC6A2 (0.35) | SMN1; SMN2SLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL13263 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2SLC6A2SLC6A4KCNH2CHRM5 | |
| SCHEMBL14142349 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2SLC6A2SLC6A4KCNH2 | |
| Bromide SCHEMBL2354969 | 0.77 | LMNA (0.38) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527051-B1 | Quinophthalone dyes, ink composition and transfer sheet containing them | MITSUI CHEMICALS INC (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5387686-A | Sublimable, yellow quinoline derivatives; storage stable; heat light, chemical resistant | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-07 | — | — | US | disclosed |
| US-5296445-A | Quinoline dyes | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0527051-A1 | Quinophthalone dyes, ink composition and transfer sheet containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-02-10 | — | — | EP | disclosed |