Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042875 | 0.96 | KCNH2 (0.40) | KCNH2FFAR1FFAR4HSD17B10TSHR | |
| SCHEMBL8041001 | 0.91 | KCNH2 (0.36) | KCNH2FFAR1GRM5 | |
| SCHEMBL8046478 | 0.87 | KCNH2 (0.40) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL8040883 | 0.86 | FFAR1 (0.35) | KCNH2FFAR1GRM5ALDH1A1MAPT | |
| SCHEMBL8039093 | 0.86 | KCNH2 (0.49) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL8039292 | 0.85 | FFAR1 (0.42) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL8046345 | 0.84 | KCNH2 (0.52) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL8046422 | 0.83 | KCNH2 (0.40) | KCNH2FFAR1FFAR4GRM5RARB | |
| SCHEMBL8039112 | 0.82 | FFAR1 (0.37) | KCNH2FFAR1GRM5ALDH1A1MAPT | |
| SCHEMBL8046343 | 0.82 | KCNH2 (0.49) | KCNH2FFAR1FFAR4MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |