SCHEMBL8040130

SCHEMBL8040130

C=CC(=O)OCCCCCOc1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.81
TSHR P16473 2/20 0.63
ALDH1A1 P00352 2/20 0.63
CYP3A4 P08684 1/20 0.63
KCNA3 P22001 1/20 0.53
HTT P42858 3/20 0.52
HDAC1 Q13547 4/20 0.51
HDAC2 Q92769 4/20 0.51
HPGD P15428 1/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
MMP2 P08253 2/20 0.48
MMP9 P14780 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16893675 1.00 THRB (0.81) THRBTSHRALDH1A1CYP3A4KCNA3
SCHEMBL16893811 1.00 THRB (0.81) THRBTSHRALDH1A1CYP3A4KCNA3
SCHEMBL26121913 1.00 THRB (0.81) THRBTSHRALDH1A1CYP3A4KCNA3
SCHEMBL16893939 1.00 THRB (0.81) THRBTSHRALDH1A1CYP3A4KCNA3
SCHEMBL16893828 1.00 THRB (0.81) THRBTSHRALDH1A1CYP3A4KCNA3
SCHEMBL8040124 1.00 THRB (0.81) THRBTSHRALDH1A1CYP3A4KCNA3
SCHEMBL1031149 0.98 THRB (0.84) THRBTSHRALDH1A1CYP3A4KCNA3
SCHEMBL69211 0.95 THRB (0.84) THRBTSHRALDH1A1CYP3A4KCNA3
Phthalic Acid SCHEMBL8659365 0.93 THRB (0.70) THRBTSHRALDH1A1CYP3A4KCNA3
SCHEMBL21940803 0.93 THRB (0.70) THRBTSHRALDH1A1CYP3A4KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
US-5198303-A Paintable high specific adhesion polyvinyl halide copolymer compositions THE B. F. GOODRICH COMPANY (US) 1993-03-30 US claimed
CN-115785735-B High-refractive-index ink for pure organic ink-jet printing and preparation method thereof 西安思摩威新材料有限公司 2024-04-26 CN disclosed
CN-117106374-A Glue composition and cured film formed by same 西安思摩威新材料有限公司 2023-11-24 CN disclosed
CN-115785735-A High-refractive-index ink for pure organic ink-jet printing and preparation method thereof 西安思摩威新材料有限公司 2023-03-14 CN disclosed
CN-115558429-A Glue composition and cured film formed by same 西安思摩威新材料有限公司 2023-01-03 CN disclosed
EP-2762506-B1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORP (JP) 2022-09-07 EP disclosed
US-10670796-B2 Organic-inorganic hybrid composition, optical member and optical device prepared using the same LMS CO., LTD. (KR) 2020-06-02 US disclosed
WO-2019151549-A1 HIGH REFRACTIVE INDEX ACRYLIC MONOMER AND PHOTOCURABLE COMPOSITION USING SAME 에스엠에스주식회사 2019-08-08 WO disclosed
US-9708424-B2 (Meth)acryloyl-terminated polyisobutylene polymer, method for producing the same, and active energy ray-curable composition KANEKA CORPORATION (JP) 2017-07-18 US disclosed
US-20170051093-A1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING THE SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORP (JP) 2017-02-23 US disclosed
US-9512247-B2 (Meth)acryloyl-terminated polyisobutylene polymer, method for producing the same, and active energy ray-curable composition KANEKA CORPORATION (JP) 2016-12-06 US disclosed
US-20160070053-A1 ORGANIC-INORGANIC HYBRID COMPOSITION, OPTICAL MEMBER AND OPTICAL DEVICE PREPARED USING THE SAME LMS CO., LTD. (KR) 2016-03-10 US disclosed
US-9145414-B2 1,2,4-triazine-6-carboxamide derivative TAIHO PHARMACEUTICAL CO., LTD. (JP) 2015-09-29 US disclosed
US-20150198740-A1 ORGANIC-INORGANIC HYBRID COMPOSITION, PRODUCTION METHOD FOR SAME, AND OPTICAL SHEET AND OPTICAL DEVICE OF SAME CHANGKANG CHEMICAL CO., LTD. (KR) 2015-07-16 US disclosed
US-20140343038-A1 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE TAIHO PHARMACEUTICAL CO., LTD. (JP) 2014-11-20 US disclosed
US-20140243444-A1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING THE SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORPORATION (JP) 2014-08-28 US disclosed
EP-2762476-A1 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE Taiho Pharmaceutical Co., Ltd. (JP) 2014-08-06 EP disclosed
EP-2762506-A1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION Kaneka Corporation (JP) 2014-08-06 EP disclosed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140343038-A1 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE SYK, BTK, JAK2 THRB 898/4885TSHR 828/4885ALDH1A1 3232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.