Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037118 | 1.00 | CFB (0.50) | CFBKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL8037105 | 0.99 | CFB (0.48) | CFBKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL8038950 | 0.84 | KMT2A (0.48) | KMT2AALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL8604373 | 0.80 | HTR7 (0.38) | KMT2AALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL8037080 | 0.76 | HSD17B10 (0.38) | KMT2AMEN1HSD17B10 | |
| SCHEMBL8604377 | 0.76 | KDM4E (0.31) | CFBKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL7569263 | 0.73 | GRIA1 (0.50) | — | |
| SCHEMBL7567546 | 0.73 | GRIA1 (0.50) | — | |
| SCHEMBL7568799 | 0.71 | GRIA1 (0.51) | — | |
| SCHEMBL8634867 | 0.71 | GRIN2D (0.44) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110911-A | ADMINISTERING NEUROPROTECTANT/ANTICONVULSANT TO PATIENT | WARNER-LAMBERT COMPANY (US) | 2000-08-29 | — | — | US | disclosed |