Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285169 | 0.87 | RXRA (0.31) | — | |
| SCHEMBL6290535 | 0.83 | CYP1A2 (0.33) | ALDH1A1 | |
| SCHEMBL6285712 | 0.82 | CFTR (0.33) | — | |
| SCHEMBL7820957 | 0.80 | HTR2C (0.31) | — | |
| SCHEMBL8859962 | 0.79 | PTAFR (0.35) | HDAC6PTAFRTSHRHSD11B1KIF11 | |
| SCHEMBL8676698 | 0.78 | TSHR (0.36) | HDAC6PTAFRTSHRKIF11TNKS | |
| SCHEMBL6285520 | 0.77 | PTAFR (0.33) | HDAC6PTAFRTSHRKIF11FFAR2 | |
| SCHEMBL1981936 | 0.77 | PTAFR (0.33) | HDAC6PTAFRTSHRKIF11FFAR2 | |
| SCHEMBL394693 | 0.77 | PTAFR (0.33) | HDAC6PTAFRTSHRKIF11FFAR2 | |
| Hydrochloric Acid SCHEMBL8859958 | 0.76 | TSHR (0.34) | HDAC6PTAFRTSHRKIF11TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143842-A | CONTINUOUSLY TRANSFERRING POLYOLEFIN, RESIDUAL CATALYST AND UNREACTED MONOMER TO CONDITIONING ZONE OF KNOWN VOLUME AND HEATING; CONTROLLING TRANSFER/REMOVAL OF POLYOLEFIN FROM THE ZONE TO ENABLE MONOMER REMOVAL WITHOUT OVERHEATING POLYOLEFIN | HUNTSMAN POLYMERS CORPORATION (US) | 2000-11-07 | — | — | US | claimed |
| US-5594080-A | POLYMERIZATION CATALYSIS OF METALLOCENES WITH CYCLOPENTADIENE AND METALS | LELAND STANFORD, JR. UNIVERSITY (US) | 1997-01-14 | — | — | US | claimed |