Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371428 | 0.85 | CYP2C9 (0.37) | TDP1CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL1923849 | 0.81 | TDP1 (0.41) | TDP1CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL8040536 | 0.81 | TDP1 (0.41) | TDP1CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL19253571 | 0.78 | HTR2A (0.43) | TDP1CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL9128915 | 0.78 | TDP1 (0.43) | TDP1CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL27425381 | 0.78 | ALDH1A1 (0.41) | TDP1CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL8663135 | 0.77 | CHRM2 (0.44) | TDP1CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL6663106 | 0.74 | TDP1 (0.40) | TDP1CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL15436603 | 0.74 | TDP1 (0.40) | TDP1CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL11328208 | 0.74 | ALDH1A1 (0.38) | TDP1ALDH1A1TSHRHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033471-A1 | Improved recovery and transportation of heavy crude oils | ROHM AND HAAS COMPANY (US) | 2000-09-06 | — | — | EP | disclosed |