Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053288 | 0.92 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL8051593 | 0.90 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL8053426 | 0.88 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8040638 | 0.88 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL215649 | 0.88 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8052132 | 0.88 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL8051566 | 0.87 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL8040701 | 0.87 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL8051595 | 0.87 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8051584 | 0.87 | PTGS2 (0.43) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808305-B1 | 3,4-DIARYL SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-05-03 | — | — | EP | claimed |
| EP-0808305-B1 | 3,4-DIARYL SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0808305-A1 | 3,4-DIARYL SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | disclosed |
| US-5596008-A | ANALGESICS, ANTIARTHRITIC | G. D. SEARLE & CO. (US) | 1997-01-21 | — | — | US | disclosed |
| WO-1996024585-A1 | 3,4-DIARYL SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-15 | — | — | WO | disclosed |