Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 12/20 | 0.81 |
| ▸ | HTR1B | P28222 | 10/20 | 0.81 |
| ▸ | HTR1A | P08908 | 9/20 | 0.81 |
| ▸ | HTR2A | P28223 | 5/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | HTR1F | P30939 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040759 | 1.00 | HTR1D (0.81) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL1246512 | 0.90 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL4427888 | 0.90 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL33336 | 0.90 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL40595 | 0.90 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL14861150 | 0.90 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL29356689 | 0.90 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL29835946 | 0.90 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL2458156 | 0.89 | HTR1D (0.98) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| Zolmitriptan SCHEMBL2377949 | 0.89 | HTR1D (0.98) | HTR1DHTR1BHTR1AHTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160123-A | One pot synthesis of 2-oxazolidinone derivatives | ZENECA, LTD. (GB) | 2000-12-12 | — | — | US | disclosed |
| US-5399574-A | 5-hydroxytryptamine agonists; vasoconstrictors | BURROUGHS WELLCOME CO. (US) | 1995-03-21 | — | — | US | disclosed |