Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042743 | 0.99 | SPHK1 (0.44) | SPHK1CYP2C9SPHK2MEN1KMT2A | |
| SCHEMBL8029221 | 0.90 | SPHK1 (0.42) | SPHK1CYP2C9SPHK2MEN1KMT2A | |
| SCHEMBL9333671 | 0.90 | GABRP (0.43) | SPHK1CYP2C9SPHK2MEN1KMT2A | |
| SCHEMBL8042560 | 0.89 | SPHK1 (0.44) | SPHK1CYP2C9SPHK2MEN1KMT2A | |
| SCHEMBL9332680 | 0.88 | GABRP (0.42) | SPHK1CYP2C9SPHK2MEN1KMT2A | |
| SCHEMBL9335953 | 0.88 | GABRP (0.42) | SPHK1CYP2C9SPHK2MEN1KMT2A | |
| SCHEMBL9333523 | 0.88 | GABRP (0.42) | SPHK1CYP2C9SPHK2MEN1KMT2A | |
| SCHEMBL10986599 | 0.88 | GABRP (0.44) | SPHK1CYP2C9SPHK2MEN1KMT2A | |
| SCHEMBL10986602 | 0.88 | GABRP (0.44) | SPHK1CYP2C9SPHK2MEN1KMT2A | |
| SCHEMBL10980768 | 0.87 | GABRP (0.43) | SPHK1CYP2C9SPHK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |