Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041173 | 1.00 | DRD2 (0.34) | DRD2ESR2SLC18A3IDO1LSS | |
| SCHEMBL8041171 | 1.00 | DRD2 (0.34) | DRD2ESR2SLC18A3IDO1LSS | |
| SCHEMBL8037081 | 0.91 | DRD2 (0.34) | DRD2ESR2IDO1LSSMDM2 | |
| SCHEMBL8037084 | 0.91 | DRD2 (0.34) | DRD2ESR2IDO1LSSMDM2 | |
| SCHEMBL8037086 | 0.91 | DRD2 (0.34) | DRD2ESR2IDO1LSSMDM2 | |
| SCHEMBL9136488 | 0.89 | ESR2 (0.40) | DRD2ESR2SLC18A3IDO1LSS | |
| SCHEMBL9139685 | 0.89 | ESR2 (0.40) | DRD2ESR2SLC18A3IDO1LSS | |
| SCHEMBL8518611 | 0.85 | ESR2 (0.42) | DRD2ESR2SLC18A3IDO1LSS | |
| SCHEMBL8518607 | 0.85 | ESR2 (0.42) | DRD2ESR2SLC18A3IDO1LSS | |
| SCHEMBL8518604 | 0.85 | ESR2 (0.42) | DRD2ESR2SLC18A3IDO1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497176-B1 | Four rings compounds and liquid crystal mixtures containing them | MERCK PATENT GMBH (DE) | 2000-04-05 | — | — | EP | disclosed |
| US-5478497-A | For electro-optical purposes | HOFFMANN-LA ROCHE INC. (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0497176-A2 | Four rings compounds and liquid crystal mixtures containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |