Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14537776 | 0.92 | MEN1 (0.57) | PLK1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL8038280 | 0.92 | ALDH1A1 (0.56) | PLK1SMN1; SMN2KDM4EHCAR2ALDH1A1 | |
| SCHEMBL8037864 | 0.90 | SMN1; SMN2 (0.58) | PLK1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL5696409 | 0.88 | ALDH1A1 (0.63) | SMN1; SMN2KDM4EHCAR2ALDH1A1LMNA | |
| SCHEMBL6408802 | 0.87 | ALDH1A1 (0.60) | SMN1; SMN2KDM4EHCAR2ALDH1A1LMNA | |
| SCHEMBL6580909 | 0.86 | HCAR2 (0.60) | SMN1; SMN2KDM4EHIF1AHCAR2ALDH1A1 | |
| SCHEMBL8044211 | 0.85 | HCAR2 (0.52) | PLK1SMN1; SMN2KDM4EHCAR2ALDH1A1 | |
| SCHEMBL8027749 | 0.85 | ALDH1A1 (0.50) | PLK1SMN1; SMN2KDM4EHIF1AHCAR2 | |
| SCHEMBL8044298 | 0.85 | ALDH1A1 (0.60) | SMN1; SMN2KDM4EHCAR2ALDH1A1LMNA | |
| SCHEMBL8041134 | 0.85 | HCAR2 (0.57) | SMN1; SMN2KDM4EHCAR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |