SCHEMBL8041341

SCHEMBL8041341

NCC(=O)Oc1ccccc1C=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
HPGD P15428 1/20 0.55
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PTGDR2 Q9Y5Y4 1/20 0.54
SRC P12931 3/20 0.49
LMNA P02545 3/20 0.47
KMT2A Q03164 3/20 0.47
GAA P10253 1/20 0.47
MEN1 O00255 2/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
TRIM24 O15164 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
TLR2 O60603 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27838674 0.98 ALDH1A1 (0.53) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL27562951 0.86 PTGDR2 (0.40) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4642180 0.83 ALDH1A1 (0.57) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL554848 0.81 ALDH1A1 (0.55) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4641968 0.81 ALDH1A1 (0.55) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL1200995 0.81 ALDH1A1 (0.55) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4644461 0.81 ALDH1A1 (0.55) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4642175 0.80 ALDH1A1 (0.53) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL8035805 0.80 PTGDR2 (0.49) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4647759 0.79 ALDH1A1 (0.52) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107337950-A Fluorescent paint and preparation method thereof made of bigcatkin willow aldehydes schiff bases 南京信息工程大学 2017-11-10 CN claimed
CN-102786538-B Salicylaldehyde glycine Schiff base and o-phenanthroline copper (II) coordination compound and preparation process and application thereof UNIV LIAOCHENG 2015-03-18 CN claimed
CN-117756824-A Preparation method and application of rare earth ternary complex 厦门稀土材料研究所 2024-03-26 CN disclosed
CN-107118127-B Amino-acid schiff base and its synthetic method and application 哈尔滨理工大学 2019-01-04 CN disclosed
CN-108250249-A A kind of quinoline ruthenium complex or its crystal and preparation method 温州大学新材料与产业技术研究院 2018-07-06 CN disclosed
CN-108164563-A A kind of pyridine ruthenium complex or its crystal and preparation method 温州大学新材料与产业技术研究院 2018-06-15 CN disclosed
CN-107337950-A Fluorescent paint and preparation method thereof made of bigcatkin willow aldehydes schiff bases 南京信息工程大学 2017-11-10 CN disclosed
CN-107337950-A Fluorescent paint and preparation method thereof made of bigcatkin willow aldehydes schiff bases 南京信息工程大学 2017-11-10 CN disclosed
CN-107118127-A Amino-acid schiff base and its synthetic method and application 哈尔滨理工大学 2017-09-01 CN disclosed
CN-102786538-B Salicylaldehyde glycine Schiff base and o-phenanthroline copper (II) coordination compound and preparation process and application thereof UNIV LIAOCHENG 2015-03-18 CN disclosed
CN-102786538-B Salicylaldehyde glycine Schiff base and o-phenanthroline copper (II) coordination compound and preparation process and application thereof UNIV LIAOCHENG 2015-03-18 CN disclosed
CN-102786538-B Salicylaldehyde glycine Schiff base and o-phenanthroline copper (II) coordination compound and preparation process and application thereof UNIV LIAOCHENG 2015-03-18 CN disclosed
CN-102786538-A Salicylaldehyde glycine Schiff base and o-phenanthroline copper (II) coordination compound and preparation process and application thereof UNIV LIAOCHENG 2012-11-21 CN disclosed
CN-102786538-A Salicylaldehyde glycine Schiff base and o-phenanthroline copper (II) coordination compound and preparation process and application thereof UNIV LIAOCHENG 2012-11-21 CN disclosed
US-6127381-A A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY LION BIOSCIENCE AG (DE) 2000-10-03 US disclosed