SCHEMBL8041520

SCHEMBL8041520

CC(=O)O[C@@H](C)[C@H](NC(=O)C(F)(F)F)c1ncc2sccn12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8059116 0.87 ELANE (0.33) KDM4E
SCHEMBL8053799 0.82 SSTR4 (0.33) KDM4E
SCHEMBL8041485 0.82 SSTR4 (0.33) KDM4E
SCHEMBL8052772 0.79 KDM4E (0.32) KDM4E
SCHEMBL9230640 0.77 KDM4E (0.33) KDM4E
SCHEMBL8041507 0.67 KDM4E (0.36) KDM4E
SCHEMBL8054568 0.66 SSTR4 (0.35) KDM4E
SCHEMBL8056613 0.66 KDM4E (0.31) KDM4E
SCHEMBL7971936 0.64 KDM4E (0.33) KDM4E
SCHEMBL9229660 0.63 SMN1; SMN2 (0.37) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0669336-B1 NOVEL CEPHEM DERIVATIVES MEIJI SEIKA CO (JP) 2000-05-17 EP disclosed
US-5663162-A BACTERICIDES AND ANTIBIOTICS MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-09-02 US disclosed
EP-0669336-A1 NOVEL CEPHEM DERIVATIVE MEIJI SEIKA KABUSHIKI KAISHA (JP) 1995-08-30 EP disclosed