Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.63 |
| ▸ | GRM6 | O15303 | 2/20 | 0.63 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.63 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.63 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.63 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.63 |
| ▸ | GSR | P00390 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.63 |
| ▸ | GRM5 | P41594 | 1/20 | 0.63 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.63 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.63 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.63 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.63 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.63 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.63 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.63 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.63 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041593 | 1.00 | GRM8 (0.63) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL29590846 | 0.90 | SLC1A1 (0.58) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL7451565 | 0.89 | GRM8 (0.59) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL14332215 | 0.89 | GRM8 (0.59) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL25357021 | 0.87 | ALOX15 (0.64) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL25357016 | 0.87 | ALOX15 (0.64) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL1374853 | 0.85 | SLC1A1 (0.52) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL1768540 | 0.85 | GSR (0.52) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL1512875 | 0.85 | SLC1A1 (0.52) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL1768542 | 0.85 | GSR (0.52) | GRM8GRM6GRM7GRM4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127165-A | NUCLEIC ACID WHICH ENCODES ENZYME HAVING DEFINED AMINO ACID SEQUENCE; USED TO PREPARE GLUTATHIONE ANALOGS AND ANTIBODIES AGAINST ENZYME, DETECT GENE IN ANIMALS, MODIFY ENZYME PRODUCTION, CONSTRUCT MODELS FOR EVALUATION OF THERAPIES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-10-03 | — | — | US | disclosed |