Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.40 |
| ▸ | AURKA | O14965 | 5/20 | 0.37 |
| ▸ | KDR | P35968 | 5/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041857 | 1.00 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL8041866 | 0.86 | HTR3E (0.52) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL8053516 | 0.85 | KMT2A (0.47) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL8052447 | 0.85 | MAPT (0.47) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL8052530 | 0.82 | KMT2A (0.46) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL8051518 | 0.82 | KMT2A (0.53) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL8052438 | 0.81 | KMT2A (0.50) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL8046746 | 0.80 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL8046941 | 0.80 | KMT2A (0.44) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL8040109 | 0.79 | KMT2A (0.56) | KMT2AMAPTMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085978-A1 | BRIDGED CARBOCYCLIC OXIME HEPATITIS C VIRUS SERINE PROTEASE INHIBITORS | ENANTA PHARCEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |