SCHEMBL8041872

SCHEMBL8041872

OCc1cc2ccc3cccc4c(O)cc(c1)c2c34

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.44
ERBB2 P04626 1/20 0.44
FYN P06241 1/20 0.44
MAOA P21397 1/20 0.44
ACHE P22303 1/20 0.44
AHR P35869 1/20 0.44
TDP1 Q9NUW8 4/20 0.42
KDM4E B2RXH2 3/20 0.42
TRPM4 Q8TD43 1/20 0.40
ALDH1A1 P00352 6/20 0.39
HPGD P15428 6/20 0.39
HSD17B10 Q99714 5/20 0.39
THRB P10828 3/20 0.39
AKR1B1 P15121 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP3A4 P08684 3/20 0.38
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALOX15 P16050 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589319 0.86 CYP1A2 (0.57) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2047161 0.86 CYP1A2 (0.57) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL9609744 0.84 TDP1 (0.55) CYP1A2ERBB2FYNMAOAACHE
Kojic Acid SCHEMBL15468029 0.83 DAO (0.51) KDM4E
SCHEMBL10824199 0.82 ERN1 (0.40) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL9642452 0.79 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL22170103 0.78 CYP1A2 (0.53) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL22651451 0.75 ACHE (0.46) CYP1A2ACHETDP1KDM4EALDH1A1
SCHEMBL2806194 0.74 NQO2 (0.57) CYP1A2ACHEKDM4ETRPM4ALDH1A1
SCHEMBL975512 0.74 CYP1A2 (0.53) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230079706-A1 Solid Cleansing Compositions and Methods for the Same COLGATE-PALMOLIVE COMPANY (US) 2023-03-16 US claimed
CN-101765432-A AGE deglycation BASF BEAUTY CARE SOLUTIONS F 2010-06-30 CN claimed
CN-1578658-A Metal organic antitumor agent VALIERI TATARSKY (UZ) 2005-02-09 CN claimed
CN-1151102-A Water-absorbent sheet for preventing discoloration of vegetable, fruit and cut-flower ASAHI CHEMICAL IND (JP) 1997-06-04 CN claimed
CN-117462466-A Skin care product raw material containing peony root bark extract and preparation method thereof 菏泽尧舜牡丹生物科技有限公司 2024-01-30 CN disclosed
CN-117025638-A Gene Aokap3 for improving kojic acid yield of aspergillus oryzae, method and application 江西科技师范大学 2023-11-10 CN disclosed
CN-110407786-B Environment-friendly and energy-saving kojic acid extraction method 四川华迈科技发展有限公司 2023-08-22 CN disclosed
CN-114045293-B Gene Aokap1 for improving kojic acid yield of aspergillus oryzae, method and application 江西省农业科学院园艺研究所 2023-06-30 CN disclosed
CN-110156733-B Tyrosinase inhibitor and application thereof 广东伊康纳斯生物医药科技股份有限公司 2023-06-16 CN disclosed
CN-116211736-A Beauty and freckle-removing liquid 黄静 2023-06-06 CN disclosed
US-20230079706-A1 Solid Cleansing Compositions and Methods for the Same COLGATE-PALMOLIVE COMPANY (US) 2023-03-16 US disclosed
CN-110538092-B Whitening and moisturizing alginate mask and preparation method thereof 南通大学 2022-10-25 CN disclosed
CN-1209168-C Micropowder functional material production AKIIRUKOO KK (JP) 2005-07-06 CN disclosed
CN-1578658-A Metal organic antitumor agent VALIERI TATARSKY (UZ) 2005-02-09 CN disclosed
CN-1439430-A Micropowder functional material production AKIIRUKOO KK (JP) 2003-09-03 CN disclosed
US-6106847-A SUNSCREEN AGENTS; SKIN SENSITIVITY LANCASTER GROUP GMBH (DE) 2000-08-22 US disclosed
CN-1151102-A Water-absorbent sheet for preventing discoloration of vegetable, fruit and cut-flower ASAHI CHEMICAL IND (JP) 1997-06-04 CN disclosed
EP-0606318-A1 VANADIUM COMPOSITIONS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1994-07-20 EP disclosed
WO-1993006811-A2 VANADIUM COMPOSITIONS COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) 1993-04-15 WO disclosed
US-4847074-A KOJIC ACID, CYCLODEXTRIN BLEND SANSHO SEIYAKU CO., LTD. (JP) 1989-07-11 US disclosed