Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039067 | 0.95 | ACACB (0.52) | ACACBCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8041089 | 0.90 | ACACB (0.48) | ACACBMCHR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL8029625 | 0.88 | ACACB (0.50) | ACACBMCHR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL8046338 | 0.84 | MCHR1 (0.52) | ACACBMCHR1 | |
| SCHEMBL8039365 | 0.84 | ACACB (0.51) | ACACBL3MBTL1LMNA | |
| SCHEMBL9514256 | 0.83 | ACACB (0.59) | ACACBMCHR1CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL8041227 | 0.83 | ACACB (0.53) | ACACBCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9335388 | 0.82 | ACACB (0.50) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8029188 | 0.81 | ACACB (0.46) | ACACBNPC1RAB9A | |
| SCHEMBL3434851 | 0.80 | ACACB (0.57) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |