Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043918 | 0.83 | MAPT (0.45) | MAPTALDH1A1POLBUSP7 | |
| SCHEMBL8032850 | 0.81 | MAPT (0.37) | MAPTALDH1A1POLBUSP7SMN1; SMN2 | |
| SCHEMBL8043892 | 0.81 | MAPT (0.38) | MAPTALDH1A1POLBUSP7SMN1; SMN2 | |
| SCHEMBL8042100 | 0.80 | MAPT (0.36) | MAPTALDH1A1USP7SMN1; SMN2 | |
| SCHEMBL8047155 | 0.80 | MAPT (0.37) | MAPTALDH1A1POLBUSP7SMN1; SMN2 | |
| SCHEMBL8043579 | 0.78 | MAPT (0.35) | MAPTALDH1A1POLBUSP7 | |
| SCHEMBL8047154 | 0.78 | MAPT (0.36) | MAPTALDH1A1POLBUSP7SMN1; SMN2 | |
| SCHEMBL5520404 | 0.77 | MAPT (0.39) | MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8046194 | 0.77 | MAPT (0.34) | MAPTALDH1A1USP7 | |
| SCHEMBL8032914 | 0.77 | MAPT (0.35) | MAPTALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |