Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047154 | 0.90 | MAPT (0.36) | MAPTALDH1A1KMT2APOLBGAA | |
| SCHEMBL8041916 | 0.89 | MAPT (0.35) | MAPTALDH1A1AGTR1AGTR2RAB9A | |
| SCHEMBL8043579 | 0.88 | MAPT (0.35) | MAPTALDH1A1POLBAGTR1AGTR2 | |
| SCHEMBL8046194 | 0.87 | MAPT (0.34) | MAPTALDH1A1USP7 | |
| SCHEMBL8032914 | 0.86 | MAPT (0.35) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL8043964 | 0.86 | MAPT (0.34) | MAPTALDH1A1USP7 | |
| SCHEMBL8034362 | 0.85 | F2 (0.39) | MAPTALDH1A1POLBUSP7 | |
| SCHEMBL8044470 | 0.85 | MAPT (0.33) | MAPTALDH1A1POLBUSP7SMN1; SMN2 | |
| SCHEMBL8044461 | 0.85 | SMN1; SMN2 (0.40) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL8043686 | 0.83 | ALDH1A1 (0.37) | MAPTALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |