Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 16/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 15/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053920 | 0.84 | AVPR1B (0.43) | KEAP1NFE2L2KCNA5TAS2R14AVPR1B | |
| SCHEMBL7342866 | 0.77 | CNR1 (0.60) | KEAP1NFE2L2KCNA5AVPR1B | |
| SCHEMBL8042851 | 0.76 | KEAP1 (0.52) | KEAP1NFE2L2KCNA5TAS2R14 | |
| SCHEMBL7359705 | 0.76 | KEAP1 (0.56) | KEAP1NFE2L2KCNA5AVPR1BMEP1B | |
| SCHEMBL3503903 | 0.72 | KEAP1 (0.76) | KEAP1NFE2L2TAS2R14MEP1B | |
| SCHEMBL1629060 | 0.72 | KEAP1 (1.00) | KEAP1NFE2L2 | |
| SCHEMBL7158517 | 0.70 | MCL1 (0.46) | — | |
| SCHEMBL7004297 | 0.70 | KEAP1 (0.89) | KEAP1NFE2L2 | |
| SCHEMBL10978183 | 0.68 | ATM (0.41) | — | |
| SCHEMBL7349521 | 0.68 | CNR1 (0.47) | KEAP1NFE2L2KCNA5AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063816-A | Hydroxamic acid compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |