Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050845 | 0.76 | KDM4E (0.31) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL13621245 | 0.72 | DPP4 (0.41) | MEN1KMT2ACYP1A2CYP2E1CYP3A4 | |
| SCHEMBL20814635 | 0.70 | DPP4 (0.44) | MEN1KMT2ACYP1A2CYP2E1CYP3A4 | |
| SCHEMBL2027946 | 0.70 | DPP4 (0.44) | MEN1KMT2ACYP1A2CYP2E1CYP3A4 | |
| SCHEMBL12362134 | 0.67 | PRMT6 (0.43) | MEN1KMT2ACYP1A2CYP2E1CYP3A4 | |
| SCHEMBL14586198 | 0.66 | PRMT6 (0.42) | MEN1KMT2ACYP1A2CYP2E1CYP3A4 | |
| SCHEMBL13420010 | 0.65 | CYP2A6 (0.47) | MEN1KMT2ACYP2E1CYP3A4CYP2D6 | |
| SCHEMBL45854 | 0.65 | — | — | |
| SCHEMBL14455880 | 0.64 | KMT2A (0.41) | MEN1KMT2ACYP1A2CYP2E1CYP3A4 | |
| SCHEMBL14455882 | 0.64 | KMT2A (0.41) | MEN1KMT2ACYP1A2CYP2E1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |