Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042693 | 0.85 | ALDH1A1 (0.35) | ALDH1A1LMNASMN1; SMN2HTTTP53 | |
| SCHEMBL8045604 | 0.82 | ALDH1A1 (0.34) | ALDH1A1LMNASMN1; SMN2HTTTP53 | |
| SCHEMBL8052220 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2HTTTP53 | |
| SCHEMBL8045769 | 0.80 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2HTTTP53 | |
| SCHEMBL8033852 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL8043423 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2HTTTP53 | |
| SCHEMBL8044908 | 0.78 | TP53 (0.35) | ALDH1A1LMNASMN1; SMN2HTTTP53 | |
| SCHEMBL8043940 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2HTTTP53 | |
| SCHEMBL8044672 | 0.78 | TP53 (0.32) | ALDH1A1LMNASMN1; SMN2HTTTP53 | |
| SCHEMBL8043601 | 0.77 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |