Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL28230339 | 0.93 | THRB (0.61) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL7182348 | 0.90 | RECQL (0.55) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL11294405 | 0.87 | TDP1 (0.54) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL29182462 | 0.87 | THRB (0.57) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL26130421 | 0.87 | THRB (0.57) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL2133045 | 0.86 | THRB (0.54) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| Methacrylic Acid SCHEMBL29217057 | 0.86 | THRB (0.47) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL20211002 | 0.86 | SMN1; SMN2 (0.48) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL7135684 | 0.85 | THRB (0.55) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL9840757 | 0.85 | THRB (0.55) | THRBRAB9ANPC1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107361-A | REACTING A SOLVENT-FREE HYDROXY FUNCTIONAL VINYL ADDITION COPOLYMER AND AN ISOCYANATE HAVING A FUNCTIONAL GROUP CAPABLE OF POLYMERIZATION IN PRESENCE OF ACTINIC RADIATON AND A HYDROXYFUNCTIONAL DILUENT | DSM N.V. (NL) | 2000-08-22 | — | — | US | disclosed |
| US-5847021-A | Solvent-free, radiation-curable, optical glass fiber coating composition and solvent-free method for making a solvent-free, radiation-curable, optical glass fiber coating composition | DSM N.V. (NL) | 1998-12-08 | — | — | US | disclosed |