Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043203 | 1.00 | TBXAS1 (0.66) | TBXAS1TBXA2R | |
| SCHEMBL8060910 | 1.00 | TBXAS1 (0.66) | TBXAS1TBXA2R | |
| (E)-Isbogrel SCHEMBL4060 | 0.81 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| (E)-Isbogrel SCHEMBL4061 | 0.81 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| Isbogrel SCHEMBL7766547 | 0.81 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL8056018 | 0.80 | TBXAS1 (0.88) | TBXAS1TBXA2R | |
| SCHEMBL8056022 | 0.80 | TBXAS1 (0.88) | TBXAS1TBXA2R | |
| SCHEMBL10634966 | 0.80 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL10634973 | 0.80 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| (E)-Isbogrel SCHEMBL10632111 | 0.80 | TBXAS1 (0.97) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114534-A | REACTING A KETONE DERIVATIVE OF CARBAMOYL SUBSTITUTED HETEROCYCLE WITH PHOSPHORANE, FOLLOWED BY ACIDIFICATION TO FORM AN ANTICOAGULANT | ELI LILLY AND COMPANY (US) | 2000-09-05 | — | — | US | disclosed |
| US-6075147-A | OMEGA-PHENYL-OMEGA-(3-PYRIDYL)-OMEGA-ALKENOIC ACID DERIVATIVES BEARING A CARBAMOYL SUBSTITUTED OXAZOLYL OR OXAZOLINYL GROUP ON THE PHENYL RING IS USEFUL FOR THROMBOXANE RECEPTOR ANTAGONSIM OR THROMBOXANE SYNTHASE INHIBITOR | ELI LILLY AND COMPANY (US) | 2000-06-13 | — | — | US | disclosed |
| US-6031095-A | Intermediates in the preparation of substituted alkenoic acids | ELI LILLY AND COMPANY (US) | 2000-02-29 | — | — | US | disclosed |
| US-5990308-A | Intermediates in the preparation of substituted alkenoic acids | ELI LILLY AND COMPANY (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0816361-A2 | Preparation of substituted alkenoic acids | ELI LILLY AND COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0811621-A2 | Carbamoyl substituted oxazoles as thromboxane receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-12-10 | — | — | EP | disclosed |