Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.59 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.59 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 3/20 | 0.30 |
| ▸ | PTGES | O14684 | 2/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416104 | 0.93 | SOAT2 (0.67) | SOAT2ACAT1SOAT1LMNAEPHX1 | |
| SCHEMBL8049344 | 0.93 | SOAT2 (0.67) | SOAT2ACAT1SOAT1LMNAEPHX1 | |
| SCHEMBL8042246 | 0.88 | SOAT2 (0.67) | SOAT2ACAT1SOAT1LMNAEPHX1 | |
| SCHEMBL8049436 | 0.85 | SOAT2 (0.68) | SOAT2ACAT1SOAT1LMNAEPHX1 | |
| SCHEMBL8043445 | 0.82 | SOAT2 (0.69) | SOAT2ACAT1SOAT1LMNAEPHX1 | |
| SCHEMBL24482943 | 0.76 | SOAT2 (0.62) | SOAT2ACAT1SOAT1LMNAEPHX1 | |
| SCHEMBL8086038 | 0.76 | SOAT2 (0.59) | SOAT2ACAT1SOAT1ESR1PLK1 | |
| SCHEMBL9446304 | 0.76 | SOAT2 (0.57) | SOAT2ACAT1SOAT1LMNAESR1 | |
| SCHEMBL9446292 | 0.76 | SOAT2 (0.57) | SOAT2ACAT1SOAT1LMNAESR1 | |
| SCHEMBL8043376 | 0.75 | SOAT2 (0.60) | SOAT2ACAT1SOAT1EPHX1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874812-B1 | NOVEL 2,3,5-TRIMETHYL-4-HYDROXY ANILIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | PF MEDICAMENT (FR) | 2000-04-05 | — | — | EP | claimed |