Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103969 | 1.00 | STAT3 (0.52) | STAT3SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL30662473 | 1.00 | STAT3 (0.52) | STAT3SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5940309 | 0.83 | MEN1 (0.51) | STAT3SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL29199272 | 0.80 | STAT3 (0.59) | STAT3IDO1MALT1MAOAMAOB | |
| SCHEMBL29135713 | 0.80 | STAT3 (0.53) | STAT3IDO1MALT1MAOAMAOB | |
| SCHEMBL1230608 | 0.80 | MAOA (0.54) | STAT3SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL31177969 | 0.80 | MAOA (0.54) | STAT3SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5940339 | 0.79 | SMN1; SMN2 (0.43) | STAT3SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3327381 | 0.77 | DNMT1 (0.50) | STAT3SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3330784 | 0.77 | STAT3 (0.43) | STAT3LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |