Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096546 | 0.87 | LMNA (0.44) | LMNASMN1; SMN2MAPTHSD17B1RECQL | |
| SCHEMBL8103468 | 0.83 | LMNA (0.45) | LMNASMN1; SMN2MAPTHSD17B1RECQL | |
| SCHEMBL8043790 | 0.83 | ESR1 (0.44) | LMNASMN1; SMN2MAPTHSD17B1RECQL | |
| SCHEMBL8056159 | 0.81 | LMNA (0.42) | LMNASMN1; SMN2MAPTHSD17B1RECQL | |
| SCHEMBL8043782 | 0.76 | ESR1 (0.46) | LMNASMN1; SMN2MAPTHSD17B1RECQL | |
| SCHEMBL8056868 | 0.76 | LMNA (0.45) | LMNASMN1; SMN2MAPTHSD17B1RECQL | |
| SCHEMBL8059625 | 0.75 | LMNA (0.48) | LMNASMN1; SMN2MAPTHSD17B1RECQL | |
| SCHEMBL8061512 | 0.75 | LMNA (0.47) | LMNASMN1; SMN2MAPTHSD17B1RECQL | |
| SCHEMBL8105903 | 0.74 | LMNA (0.44) | LMNASMN1; SMN2MAPTHSD17B1RECQL | |
| SCHEMBL8772099 | 0.74 | LMNA (0.42) | LMNASMN1; SMN2MAPTHSD17B1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799238-B1 | 14ALPHA,17ALPHA-C2-BRIDGED 19-NOR-PROGESTERONE DERIVATIVES | SCHERING AG (DE) | 2000-05-24 | — | — | EP | disclosed |