Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12192472 | 0.90 | DDB1 (0.34) | DDB1CRBNSCN9ANAMPT | |
| SCHEMBL12192457 | 0.90 | DDB1 (0.34) | DDB1CRBNSCN9ANAMPT | |
| SCHEMBL12192502 | 0.89 | DDB1 (0.34) | DDB1CRBNSCN9ANAMPTDPP8 | |
| SCHEMBL12217201 | 0.84 | DDB1 (0.34) | DDB1CRBNSCN9ANAMPTDPP8 | |
| SCHEMBL8052080 | 0.82 | DDB1 (0.35) | DDB1CRBNSCN9ANAMPT | |
| SCHEMBL12549189 | 0.81 | DPP8 (0.37) | DDB1CRBNNAMPTDPP8DPP9 | |
| SCHEMBL12192481 | 0.80 | — | — | |
| SCHEMBL12549469 | 0.79 | DPP8 (0.38) | DDB1CRBNDPP8DPP9DPP7 | |
| SCHEMBL3375348 | 0.75 | DDB1 (0.36) | DDB1CRBN | |
| SCHEMBL13757915 | 0.73 | DDB1 (0.36) | DDB1CRBNSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070689-A1 | BICYCLIC, C5-SUBSTITUTED PROLINE DERIVATIVES AS INHIBITORS OF THE HEPATITIS C VIRUS NS3 PROTEASE | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-04 | — | — | WO | disclosed |