SCHEMBL8043849

SCHEMBL8043849

C1CCC(OOOC2CCCCO2)OC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4C Q9H3R0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8043855 0.89 MEN1 (0.33) MEN1KMT2AKDM4C
SCHEMBL28705464 0.81 MEN1 (0.30) MEN1KMT2A
SCHEMBL10731669 0.80
SCHEMBL4610667 0.80
SCHEMBL13969981 0.80
SCHEMBL30805 0.78 MEN1 (0.33) MEN1KMT2AKDM4C
SCHEMBL11263233 0.78 MEN1 (0.33) MEN1KMT2AKDM4C
SCHEMBL28813769 0.78 MEN1 (0.33) MEN1KMT2AKDM4C
SCHEMBL23128370 0.76
SCHEMBL18834318 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0760366-B1 Prostaglandin derivatives ONO PHARMACEUTICAL CO (JP) 2000-01-26 EP disclosed
US-5698590-A TREATMENT OF PERIPHERAL CIRCULATORY DISORDERS AND ULCERS AND FOR BLOOD FLOW MAINTENANCE AFTER SURGERY ONO PHARMACEUTICAL CO., LTD. (JP) 1997-12-16 US disclosed
EP-0760366-A1 Prostaglandin derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1997-03-05 EP disclosed
EP-0161904-B1 TETRAHYDROFURANYL AND TETRAHYDROTHIENYL SUBSTITUTED ETHERS E.R. Squibb & Sons, Inc. (US) 1989-10-18 EP disclosed
US-4734426-A CARDIOVASCULAR AGENTS E. R. SQUIBB & SONS, INC. (US) 1988-03-29 US disclosed
US-4638011-A CARDIOVASCULAR DISORDERS, THROMBOLYTIC DISEASE E. R. SQUIBB & SONS, INC. (US) 1987-01-20 US disclosed
EP-0161904-A2 Tetrahydrofuranyl and tetrahydrothienyl substituted ethers E.R. Squibb & Sons, Inc. (US) 1985-11-21 EP disclosed
US-4542151-A CARDIOVASCULAR, BRONCHODILATION, ANALGESICS, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1985-09-17 US disclosed
EP-0021235-A1 Preparation of 25-hydroxycholesterol DIAMOND SHAMROCK CORPORATION (US) 1981-01-07 EP disclosed
US-3989720-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-11-02 US disclosed
US-3965115-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-22 US disclosed
US-3963753-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-15 US disclosed
US-3963752-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-15 US disclosed
US-3944595-A PROSTAGLANDIN THE UPJOHN COMPANY (US) 1976-03-16 US disclosed
US-3933897-A ANTIULCER, ASTHMA, RENAL DYSFUNCTION THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3933899-A ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3933895-A PROSTAGLANDINS, ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3933896-A ANTICOAGULANTS, ASTHMA, LABOR INDUCERS, CERVICAL DILATION THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3933898-A ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 US disclosed
US-3933900-A ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 US disclosed