Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8044043 | 1.00 | HTR1A (0.89) | HTR1AHTR1D | |
| Oxalic Acid SCHEMBL1088037 | 0.81 | HTR1A (0.59) | HTR1AHTR1D | |
| Oxalic Acid SCHEMBL8049264 | 0.80 | HTR1A (0.62) | HTR1AHTR1D | |
| Oxalic Acid SCHEMBL8049260 | 0.80 | HTR1A (0.62) | HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL8864158 | 0.77 | HTR1A (0.95) | HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL8864153 | 0.77 | HTR1A (0.95) | HTR1AHTR1D | |
| Oxalic Acid SCHEMBL8864004 | 0.74 | HTR1A (0.68) | HTR1AHTR1D | |
| Oxalic Acid SCHEMBL8864011 | 0.74 | HTR1A (0.68) | HTR1AHTR1D | |
| SCHEMBL14071743 | 0.74 | HTR1A (0.61) | HTR1AHTR1D | |
| SCHEMBL8052713 | 0.74 | HTR1A (1.00) | HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100268-A | MIGRAINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2000-08-08 | — | — | US | disclosed |
| US-5824682-A | Vasoconstrictive dihydrobenzopyran derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 1998-10-20 | — | — | US | disclosed |
| EP-0714396-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005383-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-02-23 | — | — | WO | disclosed |