Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61806 | 0.87 | ALDH1A1 (0.65) | ALDH1A1TDP1HTTHSD17B10TSHR | |
| SCHEMBL2437660 | 0.87 | ALDH1A1 (0.65) | ALDH1A1TDP1HTTHSD17B10TSHR | |
| SCHEMBL1118626 | 0.87 | ALDH1A1 (0.72) | ALDH1A1TDP1HTTHSD17B10TSHR | |
| SCHEMBL9479942 | 0.87 | ALDH1A1 (0.72) | ALDH1A1TDP1HTTHSD17B10TSHR | |
| SCHEMBL31555953 | 0.85 | ALDH1A1 (0.62) | ALDH1A1TDP1HTTHSD17B10TSHR | |
| SCHEMBL3283243 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TDP1HTTHSD17B10TSHR | |
| SCHEMBL3283246 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TDP1HTTHSD17B10TSHR | |
| SCHEMBL28548778 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TDP1HTTHSD17B10TSHR | |
| Methylamine SCHEMBL27714819 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TDP1HTTHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL29087184 | 0.80 | ALDH1A1 (0.63) | ALDH1A1TDP1HTTHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726889-B1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO CO (US) | 2000-04-12 | — | — | EP | disclosed |
| EP-0696269-B1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO CO (US) | 1999-06-30 | — | — | EP | disclosed |
| US-5633407-A | Process for preparing substituted aromatic amines | FLEXSYS AMERICA L. P. (US) | 1997-05-27 | — | — | US | disclosed |
| US-5618979-A | REACTING NUCLEOPHILIC AMINE AND AMIDE WITH SUBSTITUTED AROMATIC AZO COMPOUND OR AZOXY OR HYDRAZINO COMPOUND | FLEXSYS AMERICA L. P. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0641313-B1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO CO (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5552531-A | USED IN THE PRODUCTION OF AROMATIC AMINES, REACTING A NUCLEOPHILIC ANILINE, OR AMIDE OR AMINE WITH AN AZO COMPOUND | MONSANTO COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0696269-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5451702-A | Process for preparing substituted aromatic amines | MONSANTO COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0641313-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES. | MONSANTO CO (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5382691-A | Process for preparing substituted aromatic amines | MONSANTO COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| WO-1994025425-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO COMPANY (US) | 1994-11-10 | — | — | WO | disclosed |
| WO-1993024450-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES | MONSANTO COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |