Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074402 | 1.00 | MCL1 (0.34) | MCL1GABRA1GABRG2GABRB3RAB9A | |
| SCHEMBL8083169 | 1.00 | MCL1 (0.34) | MCL1GABRA1GABRG2GABRB3RAB9A | |
| SCHEMBL8074499 | 0.87 | IDO1 (0.40) | MCL1 | |
| SCHEMBL8081964 | 0.81 | CYP1A2 (0.41) | MCL1 | |
| SCHEMBL8088062 | 0.81 | CYP1A2 (0.41) | MCL1 | |
| Oxalic Acid SCHEMBL8082694 | 0.81 | MCL1 (0.39) | MCL1RAB9A | |
| SCHEMBL8081896 | 0.81 | CYP1A2 (0.41) | MCL1 | |
| Hydrochloric Acid SCHEMBL8083178 | 0.80 | CYP1A2 (0.40) | MCL1 | |
| Hydrochloric Acid SCHEMBL8083177 | 0.80 | CYP1A2 (0.40) | MCL1 | |
| SCHEMBL8038415 | 0.78 | ABL1 (0.31) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |
| US-6060508-A | FOR TREATING URINARY STRESS INCONTINENCE, GASTROINTESTINAL DISORDERS, ULCERS, MIGRAINES | SYNTHELABO (FR) | 2000-05-09 | — | — | US | disclosed |
| EP-0923567-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008834-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1998-03-05 | — | — | WO | disclosed |