SCHEMBL8074499

SCHEMBL8074499

Cc1oc2c(C(O)CN)cccc2c1C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.40
ADRA2A P08913 2/20 0.34
ADRA1A P35348 2/20 0.34
MCL1 Q07820 1/20 0.34
PNMT P11086 1/20 0.31
TAAR1 Q96RJ0 2/20 0.31
TSHR P16473 2/20 0.31
HTR3A P46098 1/20 0.31
NFKB1 P19838 1/20 0.31
HIF1A Q16665 1/20 0.31
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
ADRB2 P07550 1/20 0.30
ADRA1B P35368 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALOX15 P16050 1/20 0.30
APEX1 P27695 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL8082694 0.93 MCL1 (0.39) IDO1ADRA2AADRA1AMCL1NFKB1
SCHEMBL8083169 0.87 MCL1 (0.34) MCL1
SCHEMBL8074402 0.87 MCL1 (0.34) MCL1
SCHEMBL8044549 0.87 MCL1 (0.34) MCL1
SCHEMBL8081896 0.81 CYP1A2 (0.41) MCL1TSHR
SCHEMBL8088062 0.81 CYP1A2 (0.41) MCL1TSHR
SCHEMBL8081964 0.81 CYP1A2 (0.41) MCL1TSHR
Hydrochloric Acid SCHEMBL8083178 0.80 CYP1A2 (0.40) MCL1TSHR
Hydrochloric Acid SCHEMBL8083177 0.80 CYP1A2 (0.40) MCL1TSHR
SCHEMBL8082696 0.79 MCL1 (0.38) MCL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6063810-A ENANTIOMORPHS SYNTHELABO (FR) 2000-05-16 US disclosed