SCHEMBL8044698

SCHEMBL8044698

NCCCC(O)[C@H](N)C=O

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.39
TRPA1 O75762 1/20 0.39
GSR P00390 1/20 0.35
SPHK1 Q9NYA1 1/20 0.34
CPB2 Q96IY4 1/20 0.33
RNPEP Q9H4A4 1/20 0.30
TRPM8 Q7Z2W7 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18163483 0.82 TRPV1 (0.34) TRPV1TRPA1SPHK1PAX8
SCHEMBL17813105 0.82 TRPV1 (0.34) TRPV1TRPA1SPHK1PAX8
SCHEMBL10752238 0.78 SPHK1 (0.55) TRPV1TRPA1SPHK1
SCHEMBL18211561 0.74
SCHEMBL13387147 0.74 TRPV1 (0.48) TRPV1TRPA1GSRSPHK1CPB2
SCHEMBL10749691 0.73
SCHEMBL555028 0.70
SCHEMBL10946371 0.70
SCHEMBL8904629 0.70
SCHEMBL1044479 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0991665-A1 PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-5 RECEPTOR GLAXO GROUP LIMITED (GB) 2000-04-12 EP disclosed
WO-1998057991-A1 PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-5 RECEPTOR GLAXO GROUP LIMITED (GB) 1998-12-23 WO disclosed