⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10946371 | 1.00 | — | — | |
| SCHEMBL7145241 | 0.84 | LMNA (0.48) | — | |
| SCHEMBL11209579 | 0.84 | LMNA (0.48) | — | |
| SCHEMBL186217 | 0.84 | LMNA (0.48) | — | |
| SCHEMBL11208112 | 0.84 | LMNA (0.48) | — | |
| SCHEMBL7149767 | 0.84 | LMNA (0.48) | — | |
| SCHEMBL2225961 | 0.84 | LMNA (0.48) | — | |
| SCHEMBL2228073 | 0.82 | LMNA (0.52) | — | |
| SCHEMBL3116850 | 0.82 | LMNA (0.52) | — | |
| SCHEMBL420278 | 0.82 | LMNA (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659021-A | Chiral glycerol derivatives | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 1997-08-19 | — | — | US | disclosed |
| US-4931575-A | Chiral glycerol derivatives | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 1990-06-05 | — | — | US | disclosed |