Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MGAM | O43451 | 3/20 | 0.40 |
| ▸ | SI | P14410 | 3/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968868 | 0.84 | GAA (0.44) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL28511776 | 0.83 | ALDH1A1 (0.61) | HSD17B10ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4414586 | 0.80 | HSD17B10 (0.44) | HSD17B10ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL970105 | 0.77 | MGAM (0.43) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL29678599 | 0.77 | ALDH1A1 (0.65) | HSD17B10ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL10405791 | 0.76 | HSD17B10 (0.72) | HSD17B10ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL968285 | 0.75 | MGAM (0.66) | MAPTKMT2AMEN1GAAMGAM | |
| SCHEMBL967793 | 0.74 | MGAM (0.69) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL968154 | 0.71 | MGAM (0.43) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL966960 | 0.71 | MGAM (0.50) | HSD17B10ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |