Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 7/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | OGG1 | O15527 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | BCL2 | P10415 | 3/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | BAD | Q92934 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459279 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDATMHTR1B | |
| SCHEMBL8041636 | 0.97 | KCNA3 (0.55) | KDM4EALDH1A1HPGDATMHTR1B | |
| SCHEMBL29459162 | 0.96 | KCNA3 (0.54) | KDM4EALDH1A1HPGDATMHTR1B | |
| SCHEMBL8038193 | 0.96 | KCNA3 (0.54) | KDM4EALDH1A1HPGDATMHTR1B | |
| SCHEMBL3745947 | 0.96 | KCNA3 (0.54) | KDM4EALDH1A1HPGDATMHTR1B | |
| SCHEMBL3743455 | 0.96 | KCNA3 (0.54) | KDM4EALDH1A1HPGDATMHTR1B | |
| SCHEMBL29749590 | 0.93 | THRB (0.59) | KDM4EALDH1A1HPGDATMHTR1B | |
| SCHEMBL67466 | 0.93 | THRB (0.59) | KDM4EALDH1A1HPGDATMHTR1B | |
| SCHEMBL21312667 | 0.89 | THRB (0.55) | KDM4EALDH1A1HPGDATMHTR1B | |
| SCHEMBL12112467 | 0.89 | THRB (0.55) | KDM4EALDH1A1HPGDATMHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| US-10633549-B2 | Ink, ink accommodating container, image forming method, and image forming device | RICOH COMPANY, LTD. (JP) | 2020-04-28 | — | — | US | disclosed |
| US-20190264050-A1 | INK, INK ACCOMMODATING CONTAINER, IMAGE FORMING METHOD, AND IMAGE FORMING DEVICE | RICOH COMPANY, LTD. (JP) | 2019-08-29 | — | — | US | disclosed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | disclosed |