Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044943 | 1.00 | GRIA1 (0.40) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL8044951 | 1.00 | GRIA1 (0.40) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL8044940 | 1.00 | GRIA1 (0.40) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL8044941 | 1.00 | GRIA1 (0.40) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL6459335 | 0.95 | GRIA1 (0.42) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL6459320 | 0.95 | GRIA1 (0.42) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL6459328 | 0.95 | GRIA1 (0.42) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL91812 | 0.95 | GRIA1 (0.42) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL6459324 | 0.95 | GRIA1 (0.42) | GRIA1GRIA2GRIA3KCNH2HRH3 | |
| SCHEMBL9168970 | 0.91 | HRH3 (0.45) | GRIA1GRIA2GRIA3KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000063344-A | LIQUID CRYSTAL COMPOUND | ASAHI DENKA KOGYO KK | 2000-02-29 | — | — | JP | disclosed |