SCHEMBL8044987

SCHEMBL8044987

CCN1C(=C2SC(=S)N(c3ccc(NNC=O)cc3)C2=O)Sc2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 17/20 0.60
▸ KMT2A Q03164 17/20 0.60
▸ POLB P06746 5/20 0.56
▸ SMN1; SMN2 Q16637 4/20 0.54
▸ MAPT P10636 7/20 0.47
▸ ALDH1A1 P00352 6/20 0.47
▸ GFER P55789 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ MMP13 P45452 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.46
▸ LMNA P02545 2/20 0.44
▸ NPC1 O15118 2/20 0.44
▸ HPGD P15428 1/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ ALOX12 P18054 1/20 0.44
▸ CASP1 P29466 1/20 0.44
▸ CASP7 P55210 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ MAPK1 P28482 4/20 0.43
▸ THRB P10828 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8375382 1.00 MEN1 (0.60) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL11595549 0.90 MEN1 (0.57) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL11595546 0.90 MEN1 (0.57) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL11596193 0.84 MEN1 (0.57) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL11596191 0.84 MEN1 (0.57) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL11596758 0.83 MEN1 (0.61) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL11596754 0.83 MEN1 (0.61) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL11594949 0.83 MEN1 (0.67) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL11594944 0.83 MEN1 (0.67) MEN1KMT2APOLBSMN1; SMN2MAPT
SCHEMBL14065891 0.80 MEN1 (0.65) MEN1KMT2APOLBSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4080207-A Radiation-sensitive compositions and photographic elements containing N-(acylhydrazinophenyl) thioamide nucleating agents EASTMAN KODAK COMPANY (US) 1978-03-21 — — US claimed
EP-0653673-B1 Silver halide color photographic light-sensitive material and image-forming process KONISHIROKU PHOTO IND (JP) 2000-04-26 — — EP disclosed
EP-0588641-B1 Light-sensitive silver halide color photographic material and process for preparing color proof KONISHIROKU PHOTO IND (JP) 1999-02-10 — — EP disclosed
US-5492797-A LATENT IMAGE FORMING SILVER HALIDE GRAINS KONICA CORPORATION (JP) 1996-02-20 — — US disclosed
US-5480767-A Silver halide color photographic light-sensitive material and image-forming process KONICA CORPORATION (JP) 1996-01-02 — — US disclosed
US-5462844-A Black and white halftone dot images obtained by color separation and halftone dot image conversion, in color lithographic printing KONICA CORPORATION (JP) 1995-10-31 — — US disclosed
EP-0278666-B1 Method of making a direct positive silver halide light- sensitive photographic material KONISHIROKU PHOTO IND (JP) 1995-04-26 — — EP disclosed
EP-0636927-A1 A direct positive silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1995-02-01 — — EP disclosed
EP-0365926-B1 Direct positive light-sensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1994-08-03 — — EP disclosed
EP-0588641-A1 Light-sensitive silver halide color photographic material and process for preparing color proof KONICA CORPORATION (JP) 1994-03-23 — — EP disclosed
EP-0365926-A1 Direct positive light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1990-05-02 — — EP disclosed
US-4898807-A LONG-TERM PERFORMANCE; REDUCED FOG GENERATION KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1990-02-06 — — US disclosed
US-4868089-A ANHYDROUS HEAT TREATMENT TO INCREASE SENSITIVITY OF SILVER HALIDE EMULSION KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-09-19 — — US disclosed
US-4868102-A CORE-SHELL GRAINS, NITROGEN HETEROCYCLE PRESENT KONICA CORPORATION (JP) 1989-09-19 — — US disclosed
EP-0323747-A1 Direct-positive silver halide photographic light-sensitive material and method of processing it KONICA CORPORATION (JP) 1989-07-12 — — EP disclosed
EP-0278666-A2 Method of making a direct positive silver halide light- sensitive photographic material KONICA CORPORATION (JP) 1988-08-17 — — EP disclosed
EP-0190512-A2 Positive image forming method KONICA CORPORATION (JP) 1986-08-13 — — EP disclosed
US-4279987-A 2,5-DIHYDROXY-BIPHENYL COMPOUNDS ADDED AS DEVELOPMENT ACCELERATORS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-07-21 — — US disclosed
US-4268621-A Direct positive photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-05-19 — — US disclosed
US-4080207-A Radiation-sensitive compositions and photographic elements containing N-(acylhydrazinophenyl) thioamide nucleating agents EASTMAN KODAK COMPANY (US) 1978-03-21 — — US disclosed
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