SCHEMBL14065891

SCHEMBL14065891

CCN1/C(=C2/SC(=S)N(c3ccc(C(=O)O)cc3)C2=O)Sc2ccccc21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 13/20 0.65
▸ KMT2A Q03164 13/20 0.65
▸ SMN1; SMN2 Q16637 3/20 0.61
▸ POLB P06746 6/20 0.60
▸ MAPT P10636 4/20 0.52
▸ MMP13 P45452 1/20 0.52
▸ ALDH1A1 P00352 3/20 0.51
▸ GFER P55789 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.49
▸ LMNA P02545 2/20 0.48
▸ HPGD P15428 1/20 0.48
▸ ALOX15 P16050 1/20 0.48
▸ ALOX12 P18054 1/20 0.48
▸ CASP1 P29466 1/20 0.48
▸ CASP7 P55210 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ DUSP22 Q9NRW4 1/20 0.48
▸ NPC1 O15118 1/20 0.47
▸ PLA2G1B P04054 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596193 0.86 MEN1 (0.57) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL11596191 0.86 MEN1 (0.57) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL8044987 0.80 MEN1 (0.60) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL8375382 0.80 MEN1 (0.60) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL10036060 0.79 MEN1 (1.00) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL7019338 0.79 MEN1 (1.00) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL8887899 0.79 MEN1 (1.00) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL9191085 0.79 MEN1 (0.80) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL9191082 0.79 MEN1 (0.80) MEN1KMT2ASMN1; SMN2POLBMAPT
SCHEMBL10661708 0.78 MEN1 (0.76) MEN1KMT2ASMN1; SMN2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140235861-A1 METHOD FOR THE SYNTHESIS OF 18F-LABELLED BIOMOLECULES GE HEALTHCARE LIMITED (GB) 2014-08-21 — — US disclosed
US-7422843-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability, cinematography, uniformity for quality FUJIFILM CORPORATION (JP) 2008-09-09 — — US disclosed
US-20070248906-A1 Silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-10-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235861-A1 METHOD FOR THE SYNTHESIS OF 18F-LABELLED BIOMOLECULES GMPS, PAICS, APOBEC3C MEN1 799/4885KMT2A 2491/4885SMN1; SMN2 2449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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