Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 17/20 | 0.54 |
| ▸ | RARB | P10826 | 17/20 | 0.54 |
| ▸ | RARG | P13631 | 15/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045346 | 1.00 | RARA (0.54) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8045347 | 1.00 | RARA (0.54) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL5327179 | 0.91 | RARB (0.44) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL5327185 | 0.91 | RARB (0.44) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL5327190 | 0.91 | RARB (0.44) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8603304 | 0.88 | RARB (0.44) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8603302 | 0.88 | RARB (0.44) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8045165 | 0.85 | RARB (0.58) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7773469 | 0.77 | RARB (0.63) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL5327556 | 0.76 | RARB (0.47) | RARARARBRARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087505-A | Benzo[1,2-G]-chrom-3-ene, and benzo[1,2-G]-thiochrom-3-ene derivatives | ALLERGAN SALES, INC. (US) | 2000-07-11 | — | — | US | disclosed |