Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045659 | 1.00 | NPC1 (0.39) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8035403 | 0.94 | NPC1 (0.35) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8035407 | 0.94 | NPC1 (0.35) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8052766 | 0.91 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8052769 | 0.91 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8046131 | 0.90 | RAB9A (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8049281 | 0.90 | RAB9A (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8046129 | 0.90 | RAB9A (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8049285 | 0.90 | RAB9A (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8046951 | 0.89 | SMN1; SMN2 (0.41) | NPC1RAB9AMAPTSTAT3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643119-B1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5707547-A | CONTAINING FLUORINATED BENZENE OR NAPHTHALENE RINGS AND/OR NITROGEN CONTAINING HETEROCYCLES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0643119-A1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |