SCHEMBL80458

SCHEMBL80458

Fc1ccc(I)cc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29481423 1.00
Fluoride SCHEMBL25169957 0.97 CES2 (0.39)
Cyanide SCHEMBL28023497 0.92 CES2 (0.36)
SCHEMBL3880085 0.79
SCHEMBL1277442 0.79
SCHEMBL31621665 0.79
SCHEMBL12795395 0.78 CYP17A1 (0.47)
SCHEMBL30176409 0.77
SCHEMBL1049725 0.77
SCHEMBL12367895 0.75 MAP2K1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 618 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114031565-A N, N' -disubstituted dihydrophenazine-based compound and preparation method and application thereof 华东理工大学 2022-02-11 CN claimed
CN-112851485-B Preparation method of ticagrelor key intermediate 常州制药厂有限公司 2021-11-23 CN claimed
CN-112851485-A Preparation method of ticagrelor key intermediate 常州制药厂有限公司 2021-05-28 CN claimed
CN-108503528-B Synthetic method of anticoagulant ticagrelor intermediate raw material 韦丽 2021-02-09 CN claimed
CN-108503508-B Synthetic method of anticoagulant ticagrelor raw material intermediate 广州润霖医药科技有限公司 2021-02-02 CN claimed
CN-111072467-B Preparation method of ticagrelor key intermediate 常州制药厂有限公司 2021-01-12 CN claimed
CN-111097520-A Covalent organic framework material loaded Pd catalyst and preparation method and application thereof 中国科学院广州能源研究所 2020-05-05 CN claimed
CN-111072467-A Preparation method of ticagrelor key intermediate 常州制药厂有限公司 2020-04-28 CN claimed
CN-109485575-A A kind of preparation method of ticagrelor chiral intermediate 苏州特瑞药业有限公司 2019-03-19 CN claimed
CN-102649904-B Iridium-containing organic electroluminescent material, preparation method thereof and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2015-04-01 CN claimed
EP-1362860-B1 Method for producing tetrakis (fluoraryl)borate magnesium compound NIPPON CATALYTIC CHEM IND (JP) 2010-09-15 EP claimed
EP-1973881-A2 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES Dow Agrosciences LLC (US) 2008-10-01 EP claimed
WO-2007082098-A2 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2007-07-19 WO claimed
US-7205441-B2 Method for producing tetrakis (fluoroaryl) borate-magnesium compound NIPPON SHOKUBAI CO., LTD. (JP) 2007-04-17 US claimed
US-20030216598-A1 Method for producing tetrakis ( fluoroaryl) borate-magnesium compound NIPPON SHOKUBAI CO., LTD. (JP) 2003-11-20 US claimed
EP-1362860-A1 Method for producing tetrakis (fluoroaryl) borate magnesium compound Nippon Shokubai Co., Ltd. (JP) 2003-11-19 EP claimed
EP-4743453-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-4536344-A USING A PHOSPINE OR PHOSPHITE BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US disclosed
EP-0109606-A1 Process for the formylation of aryl halides BAYER AG (DE) 1984-05-30 EP disclosed