Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640991 | 0.93 | TDP1 (0.47) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL13811429 | 0.81 | TDP1 (0.58) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL15246779 | 0.81 | TDP1 (0.58) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL12002403 | 0.81 | TDP1 (0.58) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL27630 | 0.81 | TDP1 (0.58) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL15168182 | 0.80 | ALDH1A1 (0.57) | TDP1ALDH1A1TP53TSHRMAPT | |
| Water SCHEMBL936895 | 0.80 | TDP1 (0.56) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL13948495 | 0.79 | ALDH1A1 (0.60) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL7282257 | 0.79 | ALDH1A1 (0.60) | TDP1ALDH1A1TP53TSHRMAPT | |
| SCHEMBL11658554 | 0.79 | TDP1 (0.59) | TDP1ALDH1A1TP53TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6027849-A | SUBSTRATE COATED WITH PHOTOSENSITIVE LAYER COMPRISING A RADIATION ABSORBING MATERIAL AND POLYGLYCIDYL AZIDE CAPABLE SOLVENT-FREE RELIEF IMAGE DEVELOPMENT; PRINTING PLATES | IMATION CORP. (US) | 2000-02-22 | — | — | US | disclosed |
| EP-0562952-B1 | Ablative imageable element | MINNESOTA MINING & MFG (US) | 1996-12-27 | — | — | EP | disclosed |
| EP-0562952-A1 | Ablative imageable element | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |