Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051197 | 0.82 | ACP3 (0.41) | ACP3MMP8KDM4ECYP2C19 | |
| SCHEMBL8046123 | 0.80 | PTPN1 (0.41) | ALDH1A1KDM4EPPARGPPARACYP2C19 | |
| SCHEMBL7607484 | 0.80 | ACP3 (0.45) | ACP3ALDH1A1MMP8KDM4EHPGD | |
| SCHEMBL8061548 | 0.80 | ACP3 (0.41) | ACP3ALDH1A1MMP8KDM4EHSD17B10 | |
| SCHEMBL8423479 | 0.78 | ACP3 (0.42) | ACP3ALDH1A1MMP8KDM4EHSD17B10 | |
| SCHEMBL8046802 | 0.76 | ACP3 (0.39) | ACP3ALDH1A1HPGDCTSGPPARG | |
| SCHEMBL7609446 | 0.75 | ACP3 (0.42) | ACP3ALDH1A1MMP8KDM4EHPGD | |
| SCHEMBL7610662 | 0.74 | ACP3 (0.40) | ACP3ALDH1A1MMP8KDM4EHPGD | |
| SCHEMBL7606180 | 0.73 | ACP3 (0.41) | ACP3ALDH1A1MMP8KDM4EHPGD | |
| SCHEMBL7606875 | 0.72 | ACP3 (0.39) | ACP3KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011021-A | GLUTAMATE-DERIVED HYDROXYPHOSPHINYL DERIVATIVE. | GUILFORD PHARMACEUTICALS INC. (US) | 2000-01-04 | — | — | US | disclosed |