Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061548 | 0.87 | ACP3 (0.41) | ACP3ALDH1A1CTSG | |
| SCHEMBL5053316 | 0.85 | ACP3 (0.39) | ACP3ALDH1A1CETPPPARGPPARA | |
| SCHEMBL8059211 | 0.80 | PTPN1 (0.41) | ALDH1A1CETPPPARGPPARAMEN1 | |
| SCHEMBL7611154 | 0.80 | ACP3 (0.42) | ACP3ALDH1A1CETPPPARGPPARA | |
| SCHEMBL7608720 | 0.79 | ACP3 (0.41) | ACP3ALDH1A1CETPPPARGPPARA | |
| SCHEMBL7613491 | 0.77 | ACP3 (0.44) | ACP3ALDH1A1PPARGPPARA | |
| SCHEMBL8046097 | 0.76 | ACP3 (0.39) | ACP3ALDH1A1CTSGPPARGPPARA | |
| SCHEMBL7605240 | 0.76 | ACP3 (0.41) | ACP3ALDH1A1CTSGCETPPPARG | |
| SCHEMBL8048511 | 0.76 | ACP3 (0.42) | ACP3ALDH1A1HPGD | |
| SCHEMBL7608436 | 0.74 | CETP (0.40) | ACP3CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046180-A | NAALADase inhibitors | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-04 | — | — | US | disclosed |