Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 5/20 | 0.63 |
| ▸ | MARS1 | P56192 | 6/20 | 0.57 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8369220 | 0.99 | RPA1 (0.62) | RPA1MARS1PPP1CASMN1; SMN2P2RY14 | |
| SCHEMBL8369101 | 0.94 | RPA1 (0.61) | RPA1MARS1PPP1CASMN1; SMN2P2RY14 | |
| SCHEMBL8369875 | 0.92 | MARS1 (0.56) | RPA1MARS1PPP1CASMN1; SMN2P2RY14 | |
| SCHEMBL8369218 | 0.90 | RPA1 (0.51) | RPA1MARS1PPP1CASMN1; SMN2P2RY14 | |
| SCHEMBL8369153 | 0.89 | MARS1 (0.53) | RPA1MARS1PPP1CAMALT1 | |
| SCHEMBL8366452 | 0.89 | RPA1 (0.50) | RPA1MARS1PPP1CASMN1; SMN2P2RY14 | |
| SCHEMBL3683277 | 0.88 | PPP1CA (0.52) | RPA1MARS1PPP1CAMALT1 | |
| SCHEMBL8369874 | 0.88 | RPA1 (0.61) | RPA1MARS1PPP1CASMN1; SMN2P2RY14 | |
| SCHEMBL5902998 | 0.88 | CNR2 (0.57) | RPA1MARS1PPP1CASMN1; SMN2P2RY14 | |
| SCHEMBL8368094 | 0.87 | HDAC3 (0.50) | RPA1MARS1SMN1; SMN2P2RY14HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868420-B1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI SYNTHELABO (FR) | 2000-03-29 | — | — | EP | disclosed |
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |
| EP-0885889-A2 | Process for the preparation of pyrazole-3-carboxylic acids | SANOFI (FR) | 1998-12-23 | — | — | EP | disclosed |
| EP-0868420-A1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI (FR) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997021682-A1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI (FR) | 1997-06-19 | — | — | WO | disclosed |