SCHEMBL8046293

SCHEMBL8046293

CC#CCC1CCC(c2ccc(C#Cc3cc(F)c(CCC)c(F)c3)cc2)CC1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
ESR2 Q92731 2/20 0.32
CYP2C9 P11712 2/20 0.31
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8042621 0.91 FFAR1 (0.34) FFAR1FFAR4ESR2CYP2C9ESR1
SCHEMBL8039296 0.90 FFAR1 (0.33) FFAR1FFAR4ESR2CYP2C9ESR1
SCHEMBL8046322 0.88 FFAR1 (0.37) FFAR1FFAR4CYP2C9
SCHEMBL8039877 0.86 ESR2 (0.33) ESR2CYP2C9ESR1CYP3A4
SCHEMBL8046325 0.83 SPHK1 (0.41)
SCHEMBL8039315 0.83 SPHK1 (0.36) FFAR1FFAR4
SCHEMBL8029366 0.82 FASN (0.31) FFAR1FFAR4ESR2CYP2C9ESR1
SCHEMBL8029283 0.79 FFAR1 (0.37) FFAR1FFAR4CYP2C9
SCHEMBL8046272 0.78 GABRP (0.34) ESR2CYP2C9ESR1CYP3A4ALDH1A1
SCHEMBL8040935 0.78 ACACB (0.36) ESR2CYP2C9ESR1CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727473-B1 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-01-12 EP disclosed
US-5833879-A LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES CHISSO CORPORATION (JP) 1998-11-10 US disclosed
EP-0727473-A2 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-08-21 EP disclosed