Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 8/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.88 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3899568 | 1.00 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E | |
| Bromide SCHEMBL27692935 | 1.00 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E | |
| Bromide SCHEMBL27702129 | 1.00 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E | |
| Bromide SCHEMBL10995902 | 0.97 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E | |
| Bromide SCHEMBL80467 | 0.97 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E | |
| Bromide SCHEMBL3899564 | 0.97 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E | |
| Bromide SCHEMBL27447054 | 0.97 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E | |
| Bromide SCHEMBL30600378 | 0.97 | APOBEC3A (0.82) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E | |
| SCHEMBL12020269 | 0.97 | APOBEC3A (0.93) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E | |
| SCHEMBL147815 | 0.97 | APOBEC3A (0.93) | APOBEC3AAPOBEC3GACHEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2970 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050282-B | Method for synthesizing biodegradable plastic by using waste polyester and carbon dioxide and obtained product | 聚链科技(汕头)有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-20250248296-A1 | DEFECT ENGINEERING IN WIDE BANDGAP PEROVSKITES FOR EFFICIENT AND STABLE FULLY TEXTURED PEROVSKITE-SILICON TANDEM SOLAR CELLS | UNITED STATES DEPARTMENT OF ENERGY | 2025-07-31 | — | — | US | claimed |
| CN-120040333-A | Preparation method of 5, 6-dihydroxyindoline | 北京成宇化工有限公司 | 2025-05-27 | — | — | CN | claimed |
| EP-4347668-B1 | PROCESS FOR RECOVERING QUATERNARY SALT BROMINATION CATALYST | DDP SPECIALTY ELECTRONIC MATERIALS US LLC (US) | 2025-04-02 | — | — | EP | claimed |
| CN-119591806-A | PH responsive polymer nano micelle and preparation method and application thereof | 上海应用技术大学 | 2025-03-11 | — | — | CN | claimed |
| CN-119569601-A | Preparation method and application for efficiently preparing arformoterol tartrate intermediate | 江苏长泰药业股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-118852013-A | Preparation method of ponatinib and intermediate thereof | 武汉人福创新药物研发中心有限公司 | 2024-10-29 | — | — | CN | claimed |
| US-20240351970-A1 | PREPARATION METHOD OF 5-BROMO-2-CHLORO-BENZOIC ACID AS A SYNTHETIC RAW MATERIAL FOR HYPOGLYCEMIC DRUGS | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2024-10-24 | — | — | US | claimed |
| CN-118638091-A | Synthesis method of oxabenzo [3.2.2] bridged ring compound framework | 西南交通大学 | 2024-09-13 | — | — | CN | claimed |
| CN-118515566-A | Trimethyl phenyl ammonium tribromide and preparation method thereof | 江西天新药业股份有限公司 | 2024-08-20 | — | — | CN | claimed |
| WO-2003097622-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | GENZYME CORPORATION (US) | 2003-11-27 | — | — | WO | claimed |
| EP-0963986-B1 | 5,10-Dihydrodipyrido(2,3-b:2,3-e)pyrazine and 5,10-dihydro(2,3-b:3,2-e)pyrazine, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-04-17 | — | — | EP | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| US-6008376-A | Aminohydroxylation of olefins with tert-alkyl sulfonamides | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-12-28 | — | — | US | claimed |
| US-5929252-A | Aziridination of olefins | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-07-27 | — | — | US | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |